Chelsea will be without the services of three of his senior players when they welcome Hull City at Stamford Bridge on Friday.
The Premier League champions are hoping to record a repeat of their FA Cup final appearance last season, as they play Hull in the fifth round.
Antonio Conte will have to contend with mapping out a strategy without David Luiz, Tiemoue Bakayoko and Ross Barkley:
Conte on injuries: "Bakayoko is out, Luiz is out and Barkley is out. Then I have a couple of situations that I have to check" #CFC
— Nizaar Kinsella (@NizaarKinsella) February 15, 2018
The Blues struggled in the fourth round of the competition this season, playing two legs with Norwich City before winning via penalty shootout.
The injuries will mean the three players, before considered sure bets for Cup games, will have to wait their opportunities in the upcoming run of tough games.
Conte would have to find ways of making his team tick like they did against West Bromwich Albion in their last Premier League game, following their unexpected run of two games without a win.